7-hydroxymitragynine and morphine are substances popular for their potent pain-relieving properties. While both of them interact with the human body’s opioid receptors and provide pain relief they originate from different sources and have different mechanisms, benefits, and side effects.
In this article we will explore differences and similarities between 7-hydroxymitragynine and morphine, understanding their uses, effects, and implications.
What is 7-hydroxymitragynine?
7-hydroxymitragynine is an active terpenoid indole alkaloid found in Mitragyna speciosa, a botanical plant native to Southeast Asian countries like Thailand, Indonesia, and Malaysia. Discovered in 1994, it is a derivative of mitragynine, another compound present in kratom leaves.
7-hydroxymitragynine is known for its high potential and is mainly responsible for energizing and pain-relieving effects. It is derived naturally from kratom leaves and is known to be more potent than morphine on a per-milligram basis. This alkaloid is found in smaller amounts in kratom. It is used for pain relief, mild euphoria, relaxation, and mood enhancement.
Molecular formula: C23H30N2O5
Molecular weight: 414.50 g/mol
What is Morphine?

Morphine is a powerful opioid that is used to relieve pain and stress. It is a medication that helps manage moderate to severe body pain. Comes from the opium poppy plant, morphine has been used as a pain management medicine for decades.
Morphine is extracted from the seeds of the opium poppy. It is highly effective in chronic pain but also comes with high chances for addiction. Morphine is used in postoperative pain, cancer-related pain, and severe injury pain management.
Similarities Between 7-Hydroxymitragynine and Morphine
- Both compounds have analgesic properties which means they can help you with pain relief by rapidly acting on the central nervous system.
- Both 7-hydroxymitragynine and Morphine are made to bind with opioid receptors in the brain, mainly the mu-opioid receptor to block pain signals and provide you with a sense of relief.
- Both compounds can provide a feeling of mild euphoria. However, the intensity differs from strain to strain and dosage amount.
- Morphine has proper evidence of addiction while 7-hydroxymitragynine has a risk of dependency on prolonged use.
Key Differences Between 7-Hydroxymitragynine and Morphine
Aspect | 7-Hydroxymitragynine | Morphine |
Source | Naturally occurring in kratom. | Extracted from opium poppy resin. |
Legal Status | Legal in many regions but restricted in some. | Controlled substances in most countries. |
Addiction Risk | Lower than morphine when used responsibly. | High addiction and dependency potential. |
Side Effects | Mild nausea, dizziness, and tolerance buildup. | Severe respiratory depression, and nausea. |
Medical Use | Not FDA-approved for medical use. | Widely used in clinical settings. |
7-Hydroxymitragynine Compared to Morphine: Efficacy
- Potency: In animal studies, 7-hydroxymitragynine is more potent than Morphine approx 13-46 times. Although in kratom, it is found in very low concentrations.
- Pain Relief: Both Morphine and 7-hydroxymitragynine are effective in pain relief. But, it also depends on standardized dosing.
- Safety: Kratom is much safer than Morphine as it is a natural product that comes from trees. However, the lack of research and regulation can be a concern.
Risks and Side Effects
Below are some common side effects of 7-hydroxymitragynine and Morphine.
7-Hydroxymitragynine:
- Drowsiness.
- Dizziness.
- Nausea.
- Addiction over prolonged use.
Morphine:
- Severe constipation.
- Respiratory depression.
- Sedation.
- High Risk of Addiction
Which is Better for Pain Relief?
The choice between 7-hydroxymitragynine and morphine depends on the situation:
- For Natural Relief: 7-hydroxymitragynine is a natural alternative to pharmaceutical painkillers with fewer side effects.
- For Acute or Severe Pain: Morphine, on the other hand, is best in a medical setting as it is much standardized regarding dosing. It also has strong research backing for relieving acute or severe pain.
Where to find the best 7-Hydroxymitragynine?
7-hydroxymitragynine is available in many forms; however, tablets are the most convenient option. At Occurs Naturally, we provide premium-grade 7-OH products with concentrated dosage, crafted with care and precision to ensure the best results.
Our commitment to quality, transparency, and consumer satisfaction is what sets us apart from others. You can visit Occurs Naturally now to learn more about the benefits of our products and why we are trusted by so many.
We offer 3 types of 7-OH tablets (Relief, Energy, and Focus) in different serving sizes. These tablets give more potent and targeted effects compared to traditional kratom products, so you can enjoy potential benefits sooner and with greater intensity.
Conclusion
7-hydroxymitragynine and morphine are both strong pain relievers but with overlapping mechanisms and clear differences. While morphine is a trusted medical treatment that has been used for decades for pain management, 7-hydroxymitragynine is relatively new and offers a natural alternative that comes from plants.
People looking for a natural alternative to pharmaceutical medicine often search for 7-hydroxymitragynine. It is essential to understand the differences and similarities between morphine and 7-hydroxymitragynine for safe use during pain management. We always recommend consulting with a healthcare professional before considering these substances for pain relief.
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